SYSTEMATIC REVIEWS
SRs are highly structured explorations of literature on a narrowly defined question or perspective. Their goal is to provide measurable answers concerning treatment, policy or intervention in the clinical setting or at the public policy level
Key characteristics:
- a clearly defined research question and protocol (research plan)
- inclusion and exclusion criteria
- a rigorous and systematic search of the literature
- critical appraisal and bias assessment of all included studies
- analysis and interpretation of results
- an in-depth report
Systematic reviews are undertaken by a research team, not an individual. The team approach facilitates rapid reviewing and reduces bias.
META-ANALYSES
Are a subset of systematic reviews, a statistical technique for combining the findings from quantitative studies to come up with new statistical conclusions.
- Not all systematic reviews include meta-analysis, but all meta-analyses are found in systematic reviews.
- Systematic Reviews with meta-analysis are statistically more robust than the analysis of a single study, as they look at more subjects, have subject diversity and have more effects and results to consider.
- All included studies must be sufficiently similar for a meta-analysis to be valid.